Each daily capsule features stabilized indole-3-carbinol (I3C). a nature-identical version of the compound found in cruciferous vegetables such as broccoli. Brussels sprouts. and cabbage. I3C has the ability to promote the breakdown of estrogen to its beneficial. protective metabolite2-hydroxyestrone*. I3C may be a safe and effective way to help achieve beneficial balance in estrogen metabolism*. This product is gluten-free and vegetarian.